Aurora C (AURKC) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse testis tissue and hela cells, human liver cancer and A375 cells, 293T cells IHC: 15-50 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human AURKC
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	aurora kinase C
Database Link	NP_003151 Entrez Gene 20871 MouseEntrez Gene 6795 Human UniProt ID Q9UQB9
Background	This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Synonyms	AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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