SPAG6 Rabbit Polyclonal Antibody
CAT＃: TA350813S
Rabbit Polyclonal Anti-SPAG6 Antibody
Size: 100 ul
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Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Human testis tissue |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SPAG6 |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 55 kDa |
| Gene Name | sperm associated antigen 6 |
| Database Link | |
| Background | The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. |
| Synonyms | CT141; pf16; Repro-SA-1 |
| Reference Data | |
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