GJA8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human GJA8
Isotype	IgG
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	gap junction protein alpha 8
Database Link	NP_005258 Entrez Gene 14616 MouseEntrez Gene 29601 RatEntrez Gene 2703 Human UniProt ID P48165
Background	This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
Synonyms	CAE; CAE1; CTRCT1; CX50; CZP1; MP70
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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