DUSP26 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human DUSP26
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dual specificity phosphatase 26 (putative)
Database Link	NP_076930 Entrez Gene 66959 MouseEntrez Gene 306527 RatEntrez Gene 78986 Human UniProt ID Q9BV47
Background	DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma.
Synonyms	DSP-4; DUSP24; LDP-4; MKP-8; MKP8; NATA1; NEAP; SKRP3
Reference Data
Protein Families	Druggable Genome, Phosphatase

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