Calpastatin (CAST) Rabbit Polyclonal Antibody
CAT#: TA349734S
Rabbit Polyclonal Anti-CAST Antibody
Size: 100 ul
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CNY 6650.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Lovo cells IHC: 100-300 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CAST |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 77 kDa |
| Gene Name | calpastatin |
| Database Link | |
| Background | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Synonyms | BS-17; PLACK |
| Reference Data | |
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