AIM2 Rabbit Polyclonal Antibody

CAT#: TA349676S

Rabbit Polyclonal Anti-AIM2 Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human AIM2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name absent in melanoma 2
Background Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-©, AIM2 is thought to act as a tumor suppressor by repressing NF˚B transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of å-helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.
Synonyms PYHIN4
Reference Data
Protein Pathways Cytosolic DNA-sensing pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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