DCK Rabbit Polyclonal Antibody
CAT＃: TA349644S
Rabbit Polyclonal Anti-DCK Antibody
Size: 100 ul
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CNY 800.00
CNY 1280.00
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Mouse heart tissue IHC: 25-100 Positive control: Human tonsil Predicted cell location: Nucleus |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human DCK |
| Isotype | IgG |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 31 kDa |
| Gene Name | deoxycytidine kinase |
| Database Link | |
| Background | Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. |
| Synonyms | MGC117410; MGC138632 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Purine metabolism, Pyrimidine metabolism |
Documents
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