Nurr1 (NR4A2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human gasrtic cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human NR4A2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	nuclear receptor subfamily 4 group A member 2
Database Link	NP_006177 Entrez Gene 18227 MouseEntrez Gene 54278 RatEntrez Gene 4929 Human UniProt ID P43354
Background	This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Synonyms	HZF-3; NOT; NURR1; RNR1; TINUR
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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