Cysteine Dioxygenase Type 1 (CDO1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CDO1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CDO1.
Isotype	IgG
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CDO1 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 22 kDa; Observed: 24 kDa
Gene Name	cysteine dioxygenase type 1
Database Link	NP_001792 Entrez Gene 12583 MouseEntrez Gene 81718 RatEntrez Gene 1036 Human UniProt ID Q16878
Background	CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis (1). CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine (1,2). CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart (1). CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell (3,4).
Synonyms	cysteine dioxygenase; cysteine dioxygenase type I; type I
Reference Data
Protein Pathways	Cysteine and methionine metabolism, Metabolic pathways, Taurine and hypotaurine metabolism

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