POU2F3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3.
Isotype	IgG
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	POU2F3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 48 kDa; Observed: 55 kDa
Gene Name	POU class 2 homeobox 3
Database Link	NP_055167 Entrez Gene 18988 MouseEntrez Gene 116544 RatEntrez Gene 25833 Human UniProt ID Q9UKI9
Background	POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4).
Synonyms	Epoc-1; OCT-11; OCT11; OTF-11; PLA-1; PLA1; Skn-1a
Reference Data

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