BRG1 (SMARCA4) Rabbit Polyclonal Antibody

CAT#: TA349038

Rabbit Polyclonal Anti-SMARCA4 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen SMARCA4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SMARCA4.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification SMARCA4 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size Predicted: 185 kDa; Observed: 200 kDa
Gene Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Background The SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 4 (SMARCA4) protein, also known as BRG1, is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila (1). Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes (2). The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (3). In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44 (4,5).
Synonyms AAAT; EAAT5
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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