HCLS1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Phospho-HS1(Tyr378) Antibody: A synthesized peptide derived from human HS1 around the phosphorylation site of Tyrosine 378
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	78 kDa
Gene Name	hematopoietic cell-specific Lyn substrate 1
Database Link	NP_005326 Entrez Gene 3059 Human UniProt ID P14317
Background	Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.
Synonyms	CTTNL; HS1; lckBP1; p75
Note	Phospho-HS1(Tyr378) Antibody detects endogenous levels of HS1 only when phosphorylated at Tyrosine 378
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Pathogenic Escherichia coli infection, Tight junction

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