RIP2 (RIPK2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Phospho-RIPK2(Ser176) Antibody: A synthesized peptide derived from human RIPK2 around the phosphorylation site of Sersine 176
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70 kDa
Gene Name	receptor interacting serine/threonine kinase 2
Database Link	NP_003812 Entrez Gene 192656 MouseEntrez Gene 8767 Human UniProt ID O43353
Background	RIPK2 a tyrosine kinase-like kinase of the RIPK family. Activates pro-caspase-1 and pro-caspase-8. Potentiates casp-8-mediated apoptosis. May activate NF-kappaB. Note: This description may include information from UniProtKB.
Synonyms	CARD3; CARDIAK; CCK; GIG30; RICK; RIP2
Note	Phospho-RIPK2(Ser176) Antibody detects endogenous levels of RIPK2 only when phosphorylated at Sersine 176
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Neurotrophin signaling pathway, NOD-like receptor signaling pathway

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