MID1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-TRI18 Antibody: A synthesized peptide derived from human TRI18
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	75 kDa
Gene Name	midline 1
Database Link	NP_150632 Entrez Gene 17318 MouseEntrez Gene 54252 RatEntrez Gene 4281 Human UniProt ID O15344
Background	MID1 May have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. Belongs to the TRIM/RBCC family. A retroviral element acts as an alternative tissue- specific promoter for this gene. The LTR of an HERV-E element enhances the expression in placenta and embryonic kidney. Homodimer or heterodimer with MID2. Interacts with IGBP1. 2 isoforms of the human protein are produced by alternative splicing.
Synonyms	BBBG1; FXY; GBBB1; MIDIN; OGS1; OS; OSX; RNF59; TRIM18; XPRF; ZNFXY
Note	TRI18 antibody detects endogenous levels of total TRI18
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Ubiquitin mediated proteolysis

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