Cytokeratin 8 (KRT8) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Keratin 8 Antibody: A synthesized peptide derived from human Keratin 8
Isotype	IgG
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	55 kDa
Gene Name	keratin 8
Database Link	NP_002264 Entrez Gene 16691 MouseEntrez Gene 25626 RatEntrez Gene 3856 Human UniProt ID P05787
Background	K8 a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Phsophorylated by p38 kinase, regulating cellular keratin filament reorganization.
Synonyms	CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Note	Keratin 8 antibody detects endogenous levels of total Keratin 8
Reference Data
Protein Families	Druggable Genome

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