BAF53b (ACTL6B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA (1:500 ?? 1:1,000) ; Western blotting (1:1,000)
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-ACTL6B antibody: human ACTL6B (actin-like 6B), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein.
Isotype	IgG
Concentration	lot specific
Purification	Whole antiserum from rabbit containing 0.05% azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	actin like 6B
Database Link	NP_057272 Entrez Gene 51412 Human UniProt ID O94805
Background	ACTL6B (UniProt/Swiss-Prot entry O94805) belongs to the family of actin-related proteins (ARPs) which are involved in diverse cellular processes such as vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL6B is a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is thought to antagonize chromatin-mediated transcriptional repression thereby facilitating transcriptional activation of specific genes. Further, ACTL6B may be involved in gene regulation by structural modulation of their chromatin, specifically in the brain.
Synonyms	ACTL6; BAF53B
Reference Data
Protein Families	Druggable Genome

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