DNA PKcs (PRKDC) Mouse Monoclonal Antibody [Clone ID: 8D3-B12-F11]

Specifications

Product Data
Clone Name	8D3-B12-F11
Applications	IF, IP, WB
Recommend Dilution	WB: 1:1000, IF: 1:200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for PRKDC antibody: purified recombinant human DNA-PKcs protein fragments expressed in E.coli
Isotype	IgG2b
Formulation	Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide,50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	450 kDa
Gene Name	protein kinase, DNA-activated, catalytic polypeptide
Database Link	NP_008835 Entrez Gene 5591 Human UniProt ID P78527
Background	This gene encodes the catalytic subunit of the DNA-dependent protein kinase(DNA-PK).It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination.The protein encoded is a member of the PI3/PI4-kinase family. [provided by RefSeq,Jul 2010]
Synonyms	DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Cell cycle, Non-homologous end-joining

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