KDM5C Mouse Monoclonal Antibody [Clone ID: 2E4-E1-G8]

Specifications

Product Data
Clone Name	2E4-E1-G8
Applications	IF, WB
Recommend Dilution	WB: 1:1000, IF: 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for KDM5C antibody: purified recombinant human KDM5C / Jarid1C / SMCX protein fragments expressed in E.coli
Isotype	IgG2a
Formulation	Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	220 kDa
Gene Name	lysine demethylase 5C
Database Link	NP_004178 Entrez Gene 8242 Human UniProt ID P41229
Background	This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants.
Synonyms	DXS1272E; JARID1C; MRX13; MRXJ; MRXSCJ; MRXSJ; SMCX; XE169
Note	Detects ~38kDa. Can run up to 45kDa on SDS Page
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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