GADD45A Mouse Monoclonal Antibody [Clone ID: 6C3-G3-E9]

Specifications

Product Data
Clone Name	6C3-G3-E9
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for GADD45A antibody: purified recombinant human GADD45 a protein expressed in E.coli
Isotype	IgG1
Formulation	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22 kDa
Gene Name	growth arrest and DNA damage inducible alpha
Database Link	NP_001915 Entrez Gene 1647 Human UniProt ID P24522
Background	This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.(provided by RefSeq, Dec 2010).
Synonyms	DDIT1; GADD45
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Cell cycle, MAPK signaling pathway, p53 signaling pathway

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