FYN Mouse Monoclonal Antibody [Clone ID: 4B8-E7-A8]

Specifications

Product Data
Clone Name	4B8-E7-A8
Applications	IF, WB
Recommend Dilution	WB: 1:500, IF: 1:50
Reactivity	Human, Monkey, Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for FYN antibody: purified recombinant human Fyn protein fragments expressed in E.coli.
Isotype	IgG2b
Formulation	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59 kDa
Gene Name	FYN proto-oncogene, Src family tyrosine kinase
Database Link	NP_002028 Entrez Gene 14360 MouseEntrez Gene 25150 RatEntrez Gene 2534 Human UniProt ID P06241
Background	This gene is a member of the protein-tyrosine kinase oncogene family.It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth.The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq,Jul 2008]
Synonyms	p59-FYN; SLK; SYN
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Adherens junction, Axon guidance, Fc epsilon RI signaling pathway, Focal adhesion, Natural killer cell mediated cytotoxicity, Pathogenic Escherichia coli infection, Prion diseases, T cell receptor signaling pathway, Viral myocarditis

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