COX4 (COX4I1) Mouse Monoclonal Antibody [Clone ID: 4D11-B3-E8]

Specifications

Product Data
Clone Name	4D11-B3-E8
Applications	FC, IF, IHC, IP, WB
Recommend Dilution	WB: 1:1000, IF: 1:150, FC: 1:100
Reactivity	Human, Monkey, Mouse, Rat, Hamster, Goat
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for COX IV antibody: A synthetic peptide corresponding to carboxyl terminal residues of human COX IV
Isotype	IgG1
Formulation	Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	17 kDa
Gene Name	cytochrome c oxidase subunit 4I1
Database Link	NP_001852 Entrez Gene 12857 MouseEntrez Gene 29445 RatEntrez Gene 1327 Human UniProt ID P13073
Background	Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.The complex consists of 13 mitochondrial- and nuclear-encoded subunits.The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities.The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme.It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation,and shares a promoter with it. [provided by RefSeq,Jul 2008]
Synonyms	COX4; COX4-1; COXIV; COX IV-1; COXIV-1
Reference Data
Protein Families	Transmembrane
Protein Pathways	Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

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