MAD1 (MAD1L1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-MAD1L1 antibody is: synthetic peptide directed towards the N-terminal region of Human MAD1L1. Synthetic peptide located within the following region: EKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQ
Isotype	IgG
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	78 kDa
Gene Name	MAD1 mitotic arrest deficient like 1
Database Link	NP_003541 Entrez Gene 8379 Human UniProt ID Q9Y6D9
Background	MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
Synonyms	MAD1; PIG9; TP53I9; TXBP181
Note	Immunogen Sequence Homology: Human: 100%; Rabbit: 100%; Dog: 93%; Horse: 93%; Pig: 86%; Rat: 86%; Guinea pig: 86%; Mouse: 79%; Bovine: 79%
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle

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