GFM2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-GFM2 antibody: synthetic peptide directed towards the C terminal of human GFM2. Synthetic peptide located within the following region: TVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVE
Isotype	IgG
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	86 kDa
Gene Name	G elongation factor, mitochondrial 2
Database Link	NP_115756 Entrez Gene 84340 Human UniProt ID Q969S9
Background	Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
Synonyms	EF-G2mt; EFG2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt
Note	Immunogen Sequence Homology: Human: 100%; Dog: 93%; Pig: 86%; Horse: 86%; Bovine: 79%
Reference Data

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