Glycoprotein VI (GP6) Rabbit Polyclonal Antibody
CNY 4628.00
货期*
2周
规格
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-GP6 antibody: synthetic peptide directed towards the middle region of human GP6. Synthetic peptide located within the following region: PPSPVAEFSEATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYY |
Isotype | IgG |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 37 kDa |
Gene Name | glycoprotein VI platelet |
Database Link | |
Background | This gene encodes a platelet membrane glycoprotein ofThe immunoglobulin superfamily.The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation.The encoded protein forms a complex withThe Fc receptor gamma-chain that initiatesThe platelet activation signaling cascade upon collagen binding. Mutations inThis gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed forThis gene. [provided by RefSeq, Dec 2011] |
Synonyms | BDPLT11; GPIV; GPVI |
Note | Immunogen Sequence Homology: Human: 100% |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ECM-receptor interaction |
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