Cytokeratin 19 (KRT19) Mouse Monoclonal Antibody [Clone ID: 4E8]

Specifications

Product Data
Clone Name	4E8
Applications	ELISA, ICC/IF, IHC, WB
Recommend Dilution	Immunohistochemistry-Paraffin: 1:100-1:200, Immunocytochemistry/ Immunofluorescence: 1:25-1:200, ELISA: 1:10000, Western Blot: 1:500-1:2000, Immunohistochemistry
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human Cytokeratin 19 expressed in E. coli. [UniProt# P08727]
Isotype	IgG1
Formulation	Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41 kDa
Gene Name	keratin 19
Database Link	NP_002267 Entrez Gene 3880 Human UniProt ID P08727
Background	The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
Synonyms	CK19; K1CS; K19
Note	This Cytokeratin 19 (4E8) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Immunocytochemistry/Immunofluorescence and ELISA.
Reference Data

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