Heme Oxygenase 1 (HMOX1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC
Recommend Dilution	Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:100
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to a C-terminal portion of the human Heme Oxygenase 1 protein (between residues 225-275) [UniProt P09601]
Formulation	PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	heme oxygenase 1
Database Link	NP_002124 Entrez Gene 15368 MouseEntrez Gene 24451 RatEntrez Gene 3162 Human UniProt ID P09601
Background	HO-1 (also know as Heme oxygenase-1, HMOX1, HSP32), a member of the heme oxygenase family, is an enzyme for heme catabolism and cleaves heme to form biliverdin. This inducible protein reacts from hypoxia, cytokines, and oxidative stress. HO-1 is itself an antioxidant that protects cells from ROS (reactive oxygen species) by regulating ROS levels. HO-1 has been shown to inhibit the pathogenesis of immune related inflammatory diseases as well as cardiovascular disease (CVD).
Synonyms	bK286B10; HMOX1D; HO-1; HSP32
Note	This Heme Oxygenase 1 antibody is useful for Immunocytochemistry/Immunofluorescence and IHC-paraffin embedded sections.
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Porphyrin and chlorophyll metabolism

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