eNOS (NOS3) Mouse Monoclonal Antibody [Clone ID: 6H2]

Specifications

Product Data
Clone Name	6H2
Applications	ELISA, IHC, WB
Recommend Dilution	Immunohistochemistry-Paraffin: 1:100, Immunohistochemistry: 1:100, Western Blot: 2 ug/ml, ELISA: 1:10000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human eNOS expressed in E. coli. [UniProt# P29474]
Isotype	IgG1
Formulation	PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Ammonium sulfate precipitation
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	133 kDa
Gene Name	nitric oxide synthase 3
Database Link	NP_000594 Entrez Gene 4846 Human UniProt ID P29474
Background	eNOS (Endothelial nitric-oxide synthase), also known as NOS3, it is an important enzyme in the cardiovascular system. It is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.
Synonyms	ECNOS; eNOS
Note	This eNOS (6H2) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections and ELISA.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Arginine and proline metabolism, Calcium signaling pathway, Long-term depression, Metabolic pathways, Pathways in cancer, Small cell lung cancer, VEGF signaling pathway

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