KDM1A Mouse Monoclonal Antibody [Clone ID: 1B2E5]

Specifications

Product Data
Clone Name	1B2E5
Applications	ChIP, ELISA, IHC, Simple Western, WB
Recommend Dilution	Chromatin Immunoprecipitation (ChIP), ELISA: 1:10000, Immunohistochemistry: 1:200-1:1000, Western Blot: 1:500-1:2000, Immunohistochemistry-Paraffin: 1:200-1:1000, Simple Western: 1:500, Knockdown Validated
Reactivity	Human, Mouse, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human LSD1 (between amino acids 400-600) expressed in E. coli. [UniProt# O60341]
Isotype	IgG1
Formulation	Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	93 kDa
Gene Name	lysine demethylase 1A
Database Link	NP_001009999 Entrez Gene 99982 MouseEntrez Gene 23028 Human UniProt ID O60341
Background	The amine oxidase domain 2 AOF2 gene encodes a nuclear protein (LSD1,~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serves as a docking module for the stabilization of the associated corepressor complex(es) on chromatin.
Synonyms	AOF2; BHC110; CPRF; KDM1; LSD1
Note	This LSD1 (1B2E5) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections and ELISA.
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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