TRP1 (TYRP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Mouse, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-TYRP1 antibody: synthetic peptide directed towards the N terminal of human TYRP1. Synthetic peptide located within the following region: AKRTTHPLFVIATRRSEEILGPDGNTPQFENISIYNYFVWTHYYSVKKTF
Isotype	IgG
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Protein A purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59 kDa
Gene Name	tyrosinase related protein 1
Database Link	NP_000541 Entrez Gene 22178 MouseEntrez Gene 7306 Human UniProt ID P17643
Background	TYRP1 catalyses the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. It may regulate or influence the type of melanin synthesized.
Synonyms	b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP
Note	Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Goat: 100%; Human: 100%; Mouse: 100%; Sheep: 100%; Bovine: 100%; Rabbit: 100%; Rat: 93%; Guinea pig: 93%; Horse: 86%
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Melanogenesis, Metabolic pathways, Tyrosine metabolism

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