AIF (AIFM1) Rabbit Polyclonal Antibody
CAT＃: TA332560S
Rabbit anti-AIFM1 Polyclonal Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
Specifications
| Product Data | |
| Applications | ELISA, ICC/IF, IHC, IP, WB |
| Recommend Dilution | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
| Predicted Protein Size | 67kDa |
| Gene Name | apoptosis inducing factor, mitochondria associated 1 |
| Database Link | |
| Background | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |
| Synonyms | AIF; CMT2D; CMTX4; COWCK; COXPD6; NADMR; NAMSD; PDCD8 |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
AIFM1 mouse monoclonal antibody,clone OTI4E6, Biotinylated
AIFM1 mouse monoclonal antibody,clone OTI4E6, HRP conjugated
AIFM1 mouse monoclonal antibody,clone OTI8B8, Biotinylated
AIFM1 mouse monoclonal antibody,clone OTI8B8, HRP conjugated
AIFM1 mouse monoclonal antibody,clone OTI5D2, Biotinylated
AIFM1 mouse monoclonal antibody,clone OTI5D2, HRP conjugated
