Glypican 3 (GPC3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, FC, ICC/IF, WB
Recommend Dilution	WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 FC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	66kDa
Gene Name	glypican 3
Database Link	NP_004475 Entrez Gene 14734 MouseEntrez Gene 25236 RatEntrez Gene 2719 Human UniProt ID P51654
Background	Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Synonyms	DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1
Reference Data
Protein Families	Druggable Genome

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