Filamin A (FLNA) Mouse Monoclonal Antibody [Clone ID: 1273CT424.104.153]

Specifications

Product Data
Clone Name	1273CT424.104.153
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified His-tagged FLNA protein was used to produced this monoclonal antibody.
Isotype	IgG1
Formulation	PBS with 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	filamin A
Database Link	NP_001447 Entrez Gene 293860 RatEntrez Gene 2316 Human UniProt ID P21333
Background	Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
Synonyms	ABP-280; ABPX; CSBS; CVD1; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD
Reference Data
Protein Pathways	Focal adhesion, MAPK signaling pathway

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