WDHD1 Mouse Monoclonal Antibody [Clone ID: 20G10]

Specifications

Product Data
Clone Name	20G10
Applications	IHC, WB
Recommend Dilution	WB, IHC
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant (partial), C-terminal
Isotype	IgG2a, kappa
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	126 kD
Gene Name	WD repeat and HMG-box DNA binding protein 1
Database Link	NP_009017 Entrez Gene 218973 MouseEntrez Gene 11169 Human UniProt ID O75717
Background	The 20G10 monoclonal antibody recognizes both human and mouse AND-1 (WDHD1) also known as WD repeat and HMG box DNA binding protein 1, acidic nucleoplasmic DNA-binding protein 1. AND-1 (WDHD1) is a nuclear and nucleolar protein that contains multiple WD40 repeats, and one HMG region. AND-1 (WDHD1) has a predicted molecular weight of 126 kD and can form homodimers. WDHD1 is expressed in the brain, epidermis, liver, and stomach. During mitosis, AND-1 (WDHD1) is transiently expressed in nucleoplasm. AND-1 (WDHD1) can bind to DNA with high affinity and may be involved in protein-protein interactions. The role of AND-1 (WDHD1) is thought to be chromatin assembly, transcription and DNA replication. AND-1 (WDHD1) has been reported to be phosphorylated on S1041. The 20G10 antibody has been shown to be useful for Western blotting.
Synonyms	AND-1; AND1; CHTF4; CTF4
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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