COX15 Mouse Monoclonal Antibody [Clone ID: 7H8.2C12]

Specifications

Product Data
Clone Name	7H8.2C12
Applications	WB
Recommend Dilution	WB
Reactivity	Broad
Host	Mouse
Clonality	Monoclonal
Immunogen	Horse cyt c-OVA
Isotype	IgG2a, kappa
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	15 kD
Gene Name	COX15 cytochrome c oxidase assembly homolog
Database Link	NP_004367 Entrez Gene 1355 Human UniProt ID Q7KZN9
Background	Cytochrome c is a 15 kD protein found in the mitochondrial intermembrane space with a heme-binding domain. Cytochrome c is a component of the electron transport chain; the heme group transfers electrons from cytochrome b-c1 complex to cytochrome oxidase complex. Cytochrome c initiates apoptosis by release to cytoplasm and binding Apaf-1 which activates procaspase 9. Cytochrome c interacts with the cytochrome b-c1 complex, cytochrome oxidase complex, heme, Apaf-1, and Caspase 9 proteins. The 7H8.2C12 monoclonal antibody recognizes cytochrome-c from most species and has been shown to be useful for Western blotting.
Synonyms	CEMCOX2
Reference Data
Protein Families	Transmembrane
Protein Pathways	Metabolic pathways, Oxidative phosphorylation, Porphyrin and chlorophyll metabolism

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