COX15 Mouse Monoclonal Antibody [Clone ID: 6H2.B4]

Specifications

Product Data
Clone Name	6H2.B4
Applications	IF, IP
Recommend Dilution	IP, ICFC, IF, ICC
Reactivity	Mouse, Rat, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Rat cyt c-OVA
Isotype	IgG1, kappa
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	15 kD
Gene Name	COX15 cytochrome c oxidase assembly homolog
Database Link	NP_004367 Entrez Gene 226139 MouseEntrez Gene 309391 RatEntrez Gene 1355 Human UniProt ID Q7KZN9
Background	Cytochrome c is a 15 kD protein found in the mitochondrial intermembrane space with a heme-binding domain. Cytochrome c is a component of the electron transport chain; the heme group transfers electrons from cytochrome b-c1 complex to cytochrome oxidase complex. Cytochrome c initiates apoptosis by release to cytoplasm and binding Apaf-1 which activates procaspase 9. Cytochrome c interacts with the cytochrome b-c1 complex, cytochrome oxidase complex, heme, Apaf-1, and Caspase 9 proteins. The 6H2.B4 monoclonal antibody recognizes human, mouse, and rat cytochrome-c and has been shown to be useful for intracellular flow cytometric staining, Western blotting, immunoprecipitation, and immunofluorescence staining.
Synonyms	CEMCOX2
Reference Data
Protein Families	Transmembrane
Protein Pathways	Metabolic pathways, Oxidative phosphorylation, Porphyrin and chlorophyll metabolism

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