SSRP1 Mouse Monoclonal Antibody [Clone ID: 10D1]

Specifications

Product Data
Clone Name	10D1
Applications	WB
Recommend Dilution	WB, ChIP, IP, IF
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant (partial) (308-524aa)
Isotype	IgG2b, kappa
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	81 kD
Gene Name	structure specific recognition protein 1
Database Link	NP_003137 Entrez Gene 6749 Human UniProt ID Q08945
Background	SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D1 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.
Synonyms	FACT; FACT80; T160
Reference Data
Protein Families	Transcription Factors

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