hnRNP K (HNRNPK) Mouse Monoclonal Antibody [Clone ID: F45P9C7]

Specifications

Product Data
Clone Name	F45P9C7
Applications	WB
Recommend Dilution	WB
Reactivity	Human, Mouse, Rat, Rabbit, Chicken
Host	Mouse
Clonality	Monoclonal
Immunogen	Ovalbumin-conjugated synthetic Peptide SVKQYSGKFF
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51 kD
Gene Name	heterogeneous nuclear ribonucleoprotein K
Database Link	NP_002131 Entrez Gene 15387 MouseEntrez Gene 117282 RatEntrez Gene 3190 Human UniProt ID P61978
Background	hnRNP K (Heterogeneous nuclear ribonucleoprotein K) is a pre-mRNA binding protein and a component of hnRNP complexes providing substrate for pre-mRNA processing before becoming translatable mRNAs in cytoplasm. This protein containing KH domains and is ubiquitously expressed in the cytoplasm and the nucleus with a predicted molecular weight approximately 51 kD. hnRNP K expression and function are increased by epidermal growth factor (EGF). hnRNP K acts as transcriptional regulator and functions in nucleocytoplasmic shuttling, and is modified by phosphorylation (PKC δ, c-Src) and acetylation. Clone F45P9C7 has been shown to be useful for western blotting and immunohistochemistry of human, mouse, rat, rabbit and chicken hnRNP K.
Synonyms	CSBP; HNRPK; TUNP
Reference Data
Protein Pathways	Spliceosome

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