Synaptophysin (SYP) Rabbit Monoclonal Antibody [Clone ID: MRQ-40]

Specifications

Product Data
Clone Name	MRQ-40
Applications	IHC
Recommend Dilution	IHC:
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	synaptophysin
Database Link	NP_003170 Entrez Gene 6855 Human UniProt ID P08247
Synonyms	MRX96; MRXSYP
Note	Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, Paneth cells in the gastrointestinal tract, and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Anti-synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.
Reference Data
Protein Families	Secreted Protein, Transmembrane

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