S100A1 Mouse Monoclonal Antibody [Clone ID: 4C4.9]

Specifications

Product Data
Clone Name	4C4.9
Applications	IHC
Recommend Dilution	IHC: 1:50 - 1:200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Isotype	IgG2a
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	S100 calcium binding protein A1
Database Link	NP_006262 Entrez Gene 6271 Human UniProt ID P23297
Synonyms	S100; S100-alpha; S100A
Note	S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas.
Reference Data

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