Chromogranin A (CHGA) Mouse Monoclonal Antibody [Clone ID: LK2H10]

Specifications

Product Data
Clone Name	LK2H10
Applications	IHC
Recommend Dilution	IHC: 1:100 - 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Isotype	IgG1, kappa
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	chromogranin A
Database Link	NP_001266 Entrez Gene 1113 Human UniProt ID P10645
Synonyms	CGA
Note	Immunohistochemical methods have localized chromogranin in a wide variety of endocrine tissues such as the pituitary, pancreas, hypothalamus, and parathyroid. Neuroendocrine cells exhibit a fine granular immunoreactivity to anti-chromogranin. It is generally accepted that the co-expression of certain keratins and chromogranin mean neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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