CD43 (SPN) Mouse Monoclonal Antibody [Clone ID: MT1]

Specifications

Product Data
Clone Name	MT1
Applications	IHC
Recommend Dilution	IHC: 1:50 - 1:200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	sialophorin
Database Link	NP_003114 Entrez Gene 6693 Human UniProt ID P16150
Synonyms	CD43; GALGP; GPL115; LSN
Note	The literature indicates that from 70% to 90% of T-cell lymphomas and from 22% to 37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low grade lymphoma, rather than a reactive B-cell population. When anti-CD43 is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in paraffin-embedded tissue sections can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs)

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.