CD2 Mouse Monoclonal Antibody [Clone ID: MRQ-11]

Specifications

Product Data
Clone Name	MRQ-11
Applications	IHC
Recommend Dilution	IHC: 1:10 - 1:50
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Isotype	IgG1, kappa
Formulation	This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD2 molecule
Database Link	NP_001758 Entrez Gene 914 Human UniProt ID P06729
Synonyms	LFA-2; SRBC; T11
Note	CD2 is one of the earliest T-cell lineage restricted antigens to appear during T-cell differentiation and only rare CD2+ cells can be found in the bone marrow. Anti-CD2 is a pan-T-cell antigen marker.Anti-CD2 is therefore useful for the identification of virtually all normal T-lymphocytes. It is also very useful in the assessment of lymphoid malignancies as it is expressed in the majority of precursor and mature T-cell lymphomas and leukemias. As with other pan-T-cell antigens, CD2 may be aberrantly deleted in some neoplastic T-cell populations, especially peripheral T-cell lymphomas. When combined with anti-CD25, anti-CD2 may assist in the diagnosis of systemic mastocytosis and mastocytic leukemia.
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs), Hematopoietic cell lineage

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