BAIAP2 Rabbit Polyclonal Antibody
CAT＃: TA327577
Rabbit anti-BAIAP2 Polyclonal Antibody
Size: 20 ul
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Specifications
| Product Data | |
| Applications | ELISA, ICC/IF, WB |
| Recommend Dilution | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
| Predicted Protein Size | 61kDa |
| Gene Name | BAI1 associated protein 2 |
| Database Link | |
| Background | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Synonyms | BAP2; FLAF3; IRSP53 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Regulation of actin cytoskeleton |
Documents
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