NFAT1 (NFATC2) Rabbit Polyclonal Antibody
CAT#: TA327519
NFATC2 Rabbit Polyclonal Antibody
Size: 20 ul
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CNY 1999.00
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| Cited in 1 publication. |
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CNY 4840.00
Specifications
| Product Data | |
| Applications | ELISA, ICC/IF, IHC, WB |
| Recommend Dilution | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Formulation | Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
| Predicted Protein Size | 100kDa |
| Gene Name | nuclear factor of activated T-cells 2 |
| Database Link | |
| Background | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. |
| Synonyms | NFAT1; NFATP |
| Reference Data | |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Axon guidance, B cell receptor signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway |
Citations (1)
| The use of this Antibodies has been cited in the following citations: |
|---|
|
NFAT5 regulates renal gene expression in response to Angiotensin II through Annexin-A2-mediated post-transcriptional regulation in hypertensive rats
,Fähling, M;Paliege, A;Jönsson, S;Becirovic-Agic, M;Melville, JM;Skogstrand, T;Hultström, M;,
Am. J. Physiol. Renal Physiol.
,PubMed ID 30332317
[NFATC2]
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