LXR alpha (NR1H3) Rabbit Polyclonal Antibody
CAT＃: TA327294S
Rabbit anti-NR1H3 Polyclonal Antibody
Size: 100 ul
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CNY 800.00
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Specifications
| Product Data | |
| Applications | ELISA, WB |
| Recommend Dilution | WB,1:500 - 1:1000 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Formulation | PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
| Predicted Protein Size | 50kDa |
| Gene Name | nuclear receptor subfamily 1 group H member 3 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | LXR-a; LXRA; RLD-1 |
| Reference Data | |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | PPAR signaling pathway |
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