BTK Rabbit Polyclonal Antibody
CAT#: TA327086S
BTK Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
货期*
2周
规格
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommend Dilution | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 76kDa |
Gene Name | Bruton tyrosine kinase |
Database Link | |
Background | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Synonyms | AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency |
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