Wilms Tumor Protein (WT1) Rabbit Polyclonal Antibody
CAT#: TA326990S
WT1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
货期*
2周
规格
Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | WB,1:500 - 1:1000 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 49kDa |
Gene Name | Wilms tumor 1 |
Database Link | |
Background | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. |
Synonyms | AWT1; EWS-WT1; GUD; NPHS4; WAGR; WIT-2; WT33 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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抗体相关资料 |
其它Wilms Tumor Protein产品
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