SPNS1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	SPINSTER antibody was raised against an 18 amino acid peptide near the amino terminus of human SPINSTER.
Isotype	IgG
Formulation	SPINSTER antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	SPINSTER antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 58 kDa; Observed: 70 kDa
Gene Name	sphingolipid transporter 1 (putative)
Database Link	NP_001135920 Entrez Gene 83985 Human UniProt ID Q9H2V7
Background	SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily (1). SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death (2). The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3).
Synonyms	HSpin1; LAT; nrs; PP2030; SPIN1; SPINL
Reference Data

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