67kDa Laminin Receptor (RPSA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA.
Isotype	IgG
Formulation	RPSA antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	RPSA antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 32 kDa; Observed: 38 kDa
Gene Name	ribosomal protein SA
Database Link	NP_002286 Entrez Gene 16785 MouseEntrez Gene 3921 Human UniProt ID P08865
Background	The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2). RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3).
Synonyms	1CHD4; 37LRP; 67LR; ICAS; LAMBR; lamR; LAMR1; LBP; LR; LRP; NEM; p40; SA
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Ribosome

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