COMMD7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	COMMD7 antibody was raised against a 19 amino acid peptide near the center of human COMMD7.
Isotype	IgG
Formulation	COMMD7 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	COMMD7 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 22 kDa; Observed: 21 kDa
Gene Name	COMM domain containing 7
Database Link	NP_444269 Entrez Gene 99311 MouseEntrez Gene 296285 RatEntrez Gene 149951 Human UniProt ID Q86VX2
Background	COMMD7 (COMM domain-containing protein 7) plays a role in the regulation NF-kappaB (1). It associates with the NF-kB complex and suppresses its transcriptional activity (2). COMMD7 contains 1 COMM domain and widely expressed with highest expression in lung (3). COMMD7 is a newly identified gene overexpressed in hepatocellular carcinoma (HCC) (4). COMMD7 is associated with tumor invasion and poor prognosis by NF-kappaB signaling pathway (4).
Synonyms	C20orf92; dJ1085F17.3
Reference Data

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